ISIS is a world-leading centre for research in the physical and life sciences at the STFC Rutherford Appleton Laboratory near Oxford in the United Kingdom. Our suite of neutron and muon instruments gives unique insights into the properties of materials on the atomic scale. 

We support a national and international community of more than 3000 scientists for research into subjects ranging from clean energy and the environment, pharmaceuticals and health care, through to nanotechnology and materials engineering, catalysis and polymers, and on to fundamental studies of materials.

News and Events

News for users: October 2016 round

ISIS news, events, instrument updates and information on how to apply for beamtime for users who wish to submit a proposal in the next round.

ISIS Molecular Spectroscopy Science Meeting 2016
ISIS Molecular Spectroscopy Science Meeting 2016

Wednesday 09 November 2016

The ISIS Molecular Spectroscopy Group will hold its next science meeting at the Cosener’s House, Abingdon on the 9th and 10th of November 2016.

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ISIS Crystallography Users Meeting

Monday 31 October 2016

The ISIS Crystallography Users Meeting will take place at the Cosener's House, Abingdon on 31st October and 1st November 2016, in conjunction with the PCG-SCMP Winter Meeting

MDANSE flyer

Thursday 10 November 2016

The ISIS Molecular Spectroscopy Group and ILL Computing for Science Group will hold the next MDANSE (Molecular Dynamics and Lattice Dynamics to Analyse Neutron Scattering Experiments) workshop at the Cosener’s House, Abingdon, UK from the 10th to 12th of November 2016.

The RAL team and their robot Sweeney Todd
ISIS Graduate joins RAL Robot Wars team in battle

Monday 15 August 2016

ISIS Graduate, Jon Elmer, joined his fellow RAL Graduates to star in BBC2’s Robot Wars last night, in one of 40 teams battling it out to become the show’s 2016 champion. The RAL graduate team, completed by Laurence de Bruxelles (RAL Space), Sean Cleary (Team Captain; Technology) and Dominique Anderson (Robot Pilot; Central Laser Facility), spent four weeks staying late after work to design and build their Robot, Sweeny Todd.

The ISIS synchrotron. Credit: STFC
ISIS features in three-part series on accelerators

Wednesday 10 August 2016

The Royal Institution has produced three short films about accelerator science as part of ‘Accelerators for humanity’, a project supported by an STFC Public Engagement Large Award. The first film, released today, explores what is needed to keep the ISIS particle accelerator running and the people that make it happen.

Giorgia Albani (Universita Milano Bicocca)
ISIS Facility Development Studentships – call now open

Wednesday 10 August 2016

ISIS has available a limited number of 50%-funded studentships available to UK users to run from October 2017. A full description of this studentship scheme plus instructions on how to apply is available and the deadline for requests is 16 October 2016.

Major Instrument and Accelerator Projects

Target Station 2 Phase 2

2015 will see both the capacity and capability of ISIS increase with two new instruments coming online. Target station 2 started operation in 2008 with 7 neutron instruments, and now two new instruments, ChipIR and Larmor have received first neutrons and are beginning their commissioning phases. A further two instruments, IMAT and ZOOM, are under construction.

ISIS First Target Station Project

The ISIS First Target Station (TS1) has now been operating for over 30 years. During this period, there has been no significant work carried out to maintain or develop the internals of TS1. The ISIS First Target Station project aims to refurbish much of TS1 to ensure its continued operation for many years into the future.

TOSCA and MAPS guide projects

Design on the new guides for Maps and Tosca has started with the aim of having the upgraded instruments running sometime in 2016.

Replacement of muon beamline magnets

The ISIS muon facility has been operating since 1987, and some of the muon beamline magnets were second-hand then – they are now over 50 years old in some cases. During the long shutdown in 2014/5, the quadrupoles near the muon target will be replaced.

Linac Tank 4 Replacement

The ISIS linear accelerator (linac) consists of 4 radiofrequency (RF) accelerating tanks, accelerating hydrogen ions generated in the ion source to 37% of the speed of light before feeding them into the synchrotron for final acceleration. Tanks 1 and 4 were built at RAL in 1976, for ISIS’ predecessor, Nimrod. They are now showing their age, so a project is underway to replace tank 4 by 2018.

Refurbishing part of the first target station proton beamline (EPB1)

EPB1 is made up of 68 magnets all of which are roughly 50 years old. Many of the electrical windings of these magnets are deteriorating (especially in high radiation-dose areas near the downstream end of EPB1). Replacement of magnets upstream of the muon target and between the muon target and the neutron target will take place during the 2014/15 shutdown.

Science at ISIS

Credit: Dreamstime
How to deliver drugs across the picky blood-brain barrier

Friday 02 September 2016

Less than 2% of small molecules, including therapeutics, are able to cross the blood-brain barrier (BBB) and reach the brain from the bloodstream. The blood-brain barrier is a semi-permeable barrier that separates the extracellular fluid surrounding the brain from circulating blood. Separating the brain from the bloodstream, it protects the brain against any sort of toxins in the blood. Its protective nature is because of its high selectivity; however, this also means it is difficult to deliver therapeutics to the brain.

Reproduced from Phys. Chem. Chem. Physwith permission from PCCP
Neutron Scattering in Catalysis and Energy Materials

Monday 15 August 2016

As we move away from our dependency on fossil fuels and work towards cleaner energy resources and chemical conversion it is key to further our understanding of catalysis. Whether it’s assisting reactions in energy transformations, providing chemicals with increased efficiency or getting rid of, or preventing, waste, catalysis will help in the move towards a greener future. Progress in catalytic science and its applications requires an understanding of what is taking place with the catalyst at the molecular level, which is where techniques such as neutron scattering are invaluable.

A phase arrangement of the iron magnetic moment in calcium ferrate
Solitary magnons in calcium ferrate

Monday 08 August 2016

Materials that display localised electronic or magnetic behaviour are of wide interest in physics. One reason is that they can provide insights into unusual quantum phenomena, as seen in single molecular magnets for example. An international group of scientists have been using neutrons to study calcium ferrate to understand how different magnetic arrangements are distributed throughout the material. Surprisingly they found that the phases existed in tiny regions only a few nanometres across, containing localised waves of magnetic excitations. This discovery could lead to the use of magnetic materials in a similar fashion to photonic crystals.

Using neutrons in the development of treatments for infectious disease
Scientists gather to discuss the future of tackling infectious diseases

Thursday 04 August 2016

World-leading neutron scientists gathered last week to discuss the latest findings in the development of drugs to tackle infectious diseases and antibiotic resistance. The annual UK Neutron and Muon Science and User Meeting (NMSUM) was hosted in Warwick, UK, and brought together researchers using the neutron instruments at the ISIS Neutron and Muon Source, UK, and the Institut Laue-Langevin (ILL) in France.

Making an impact

Impact of Neutron Scattering brochure
Neutron Scattering: Materials research for modern life

Thursday 22 November 2012

Read about the social and economic impact of neutron scattering in a new brochure highlighting key examples of the use of the technique.

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