ISIS Isotope Facility
12 Oct 2009



The ISIS Isotope Facility (formerly the Oxford Isotope facility) is able to produce deuterated small molecules for ISIS and ILL experiments.


Details of what is possible are below. If you think you will need to use the services of the isotope facility for your experiment please tick the box on the ISIS proposal form when you submit a proposal, and also contact John Webster ( to discuss your requirements.

Materials categories:

Category A

Perdeuterated fatty acids of most chain lengths from C6 to C20, including odd numbered chains, and the alcohol and bromoalkane versions of these. It is envisaged that up to 10 g of any compound could be made available instantly (a case will have to be made for quantities larger than 1g).

Sodium dodecyl sulphate. Some chain deuterated alkyl trimethylammonium bromides (C12, C14, C16, enquire about others). Some chain deuterated oligoethyleneglycol monoether non-ionic surfactants (enquire).

Category B

The compounds in this category include most compounds with a straight chain alkyl group, e.g. alkyl trichlorosilanes, alkane thiols, alkane sulphonates, dialkyl dimethyl ammonium halides.

Some dicarboxylic acids (C12, enquire about others) and their corresponding dialcohols and dibromides. Ethylhexanoic acid and corresponding alcohol and bromide.

Category C

This list will be responsive to users’ requests. At this stage high priorities have been identified for perdeuterated oleic acid and perdeuterated aminoacids with hydrophobic groups (leucine, isoleucine, valine, alanine).

Category D

There are a number of smaller compounds that are widely used where a commercially favourable price could be negotiated for buying large amounts. The unit could buy these and sell on smaller quantities to the user.

Examples in this category are ethylene oxide, trimethylamine, dimethylamine, styrene, methylmethacrylate.