Dr
James
Tellam
Senior Synthetic Organic Chemist
(01235) 445785
Yes
james.tellam@stfc.ac.uk
No
RAL R80,2.02
Yes
07876-651485
Yes

​Job Role:

I work in the deuteration facility synthesising a wide range of deuterated chemicals for users, to be used in neutron experiments at ISIS​ and further a field.

Previous Studies:

Postdoctoral Research Associate, University of Strathclyde, Glasgow. ‘Innovative targets for Circadian drug discovery: REV-ERBα & RORα’ with Prof. Nicholas Tomkinson

PhD - University of Bath, An Ireland-Claisen approach to b-hydroxy a-amino acids.’ Supervisor Dr David Carbery​

​Selected Publications:

Circadian clock component REV-ERBα con​trols homeostatic regulation of pulmonary infla​mmation​​

Pariollaud, M., Gibbs, J., Begley, N. et al. J. Clin. Invest., 2018, 128, 2281.​​​

Magnetic Exchange Interactions in the Molecular Nanomagnet Mn12

Chiesa A. et al. Phys. Rev. Lett. 2017, 119, 217202.


Preparation of Symmetrical and Nonsymmetrical Fluorene ­Sulfonamide Sc​affolds​​​

Jones, D. H.; Tellam, J. P. et al. Synlett., 2017, 28, 577.

Synthesis of dibenzylamino-1-methylcyclohexanol and dibenzylamino-1-trifluoromethylcyclohexanol isomers​​

Jones, D. H.; Bresciani, S.; Tellam, J. P. et al. Org. Biomol. Chem., 2016, 14, 172.

Optimized Chemical Probes for REV-ERBα​​​​

Trump, R.P.; Bresciani, S.; Cooper, A.W.J.; Tellam, J.P. et al. J. Med. Chem., 2013, 56, 4729.

Double Gold‐Catalysed Annulation of Indoles by Enynones​​

Heffernan, S.J.; Tellam, J.P. et al. Adv. Synth. Catal., 2013, 355, 1149.

Ireland-Claisen rearrangement of substrates bearing chiral enol ether units​​

Tellam, J.P.; Carbery, D.R. Tetrahedron Lett., 2011, 52, 6027.

Development of the Ireland−Claisen Rearrangement of Alkoxy- and Aryloxy-Substituted Allyl Glycinates​​​​​​​​​​​

Tellam, J.P.; Carbery, D.R. J. Org. Chem., 2010, 75, 7809.

An Ireland−Claisen Approach to β-Alkoxy α-Amino Acids​​

Tellam, J.P.; Kociok-Köhn, G.; Carbery, D.R. Org. Lett., 2008, 10, 5199.

An Ireland–Claisen rearrangement approach to β2,3-amino acids​​

Ylioja P. et al., Tetrahedron Lett., 2008, 49, 1111​​