VISITOR SCIENTIST at Norwegian University of Science and Technology, Trondheim (since 2018)
MAIN INTERESTS:
Materials, clays, polymers, lipid membranes, mesoporous systems and gels.
PREVIOUS POSITIONS:
Institute For Energy Technology (IFE), Kjeller, Norway (2016 - 2019)
School of Chemical Engeneering, University of Campinas (Unicamp), Brazil (visitor scientist, 2015 - 2016)
Brazilian Synchrotron Light Lab, Campinas, Brazil, (beamline scientist, 2010 - 2015)
Federal University of Sao Paulo (UNIFESP), Sao Jose dos Campos, Brazil (visitor scientist, 2013 - 2015)
Institute of Pharmacy, University of Tromsoe, Norway (2008 - 2010)
Institute of Physics, University of Missouri, Columbia, United States (2007)
Institute Laue Langevin, Grenoble, France (2006)
European Synchrotron Radiation Facility, Grenoble, France (2002 - 2006)
Rhodia Brazil, Chemical Industry, Paulinia, Brazil (2001 - 2002)
PhD in Physics, University of Campinas, Brazil, 2001
ID links:
STFC ePubs Database
ORCID: 0000-0002-0408-0058
Scopus Author ID: 8855804500
FULL LIST OF PUBLICATIONS (in 2025):
Moreno Herrero, Jorge, Theo B Stahl, Stephanie Erbar, Konrad Maxeiner, Anne Schlegel, Tijana Bacic, Jens Schumacher, Cavalcanti, Leide P, Schroer, Martin A, Svergun, Dmitri I, Sahin, Ugur, Haas, Heinrich (2025). “Compact Polyethylenimine-Complexed MRNA Vaccines." Nature Nanotechnology. https://doi.org/10.1038/s41565-025-01961-w.
Jones, Mary C, Leide P Cavalcanti, Filipe Vilela, Valeria Arrighi, Gregory N Smith, Gareth O Lloyd, Robert Dalgliesh, and Stephen R Euston. 2025. “Self-Sorting and Co-Assembly Control in Multicomponent Supramolecular Hydrogels with Dual Monomer and Polymer Statistical Distribution," 1–9.
Mello, Lucas R. de, Valeria Castelletto, Leide Cavalcanti, Jani Seitsonen, and Ian W. Hamley. 2025. “Self‐Assembly of a Conjugate of Lipoic Acid With a Collagen‐Stimulating Pentapeptide Showing Cytocompatibility and Wound Healing Properties, and Chemical and Photolytic Disassembly." Journal of Peptide Science 31 (3): 1–9. https://doi.org/10.1002/psc.70002.
Amato, Zachary, Thomas F. Headen, Sabrina Gärtner, Pierre Ghesquière, Tristan G.A. Youngs, Daniel T. Bowron, Leide Cavalcanti, et al. 2025. “Using Neutrons to Ascertain the Impact of Deposition Temperature on Amorphous Solid Water." Physical Chemistry Chemical Physics, no. 1999: 6616–27. https://doi.org/10.1039/d5cp00270b.
Seljelid, K. K., Neto, O. T., Akanno, A. N., & Ceccato, B. T. (2024). P HYSICAL J OURNAL Growth kinetics and structure of a colloidal silica-based network : in situ RheoSAXS investigations. The European Physical Journal Special Topics, 123. https://doi.org/10.1140/epjs/s11734-024-01250-y
Salazar, H., Rosales, M., Zarandona, I., Serra, J., Gonçalves, B. F., Valverde, A., Cavalcanti, L. P., Lanceros-Mendez, S., García, A., de la Caba, K., Guerrero, P., Martins, P. M., & Fernández de Luis, R. (2024). Metal-Organic Framework Functionalized Chitosan/Pectin Membranes for Solar-Driven Photo-Oxidation and Adsorption of Arsenic. Chemical Engineering Journal, 497, 154417. https://doi.org/10.1016/j.cej.2024.154417
Salazar, Hugo, Bruna F. Gonçalves, Ainara Valverde, Renato Gonçalves, Carlos M. Costa, Leide P. Cavalcanti, José M. Porro, Viktor Petrenko, Senentxu Lanceros-Mendez, and Qi Zhang. 2025. “High-Performance Composite Solid-State Electrolyte Combining NASICON-Type Li1.5Al0.5Ti1.5(PO4)3 with Ionic Liquid and Polymeric Binders." Electrochimica Acta 509 (October 2024): 145299. https://doi.org/10.1016/j.electacta.2024.145299.
Le, Thu Phuong, Leide Cavalcanti, James P. Tellam, and Paula Malo de Molina. 2024. “Effect of the Protein Chain Conformation on the Collapse into Nanoparticles." Biomacromolecules. https://doi.org/10.1021/acs.biomac.4c00754.
Gonçalves, Bruna F., Eduardo Fernández, Ainara Valverde, Mattia Gaboardi, Hugo Salazar, Viktor Petrenko, José María Porro, et al. 2024. “Exploring the Compositional Space of a Metal-Organic Framework with Ionic Liquids to Develop Porous Ionic Conductors for Enhanced Signal and Selectivity in VOC Capacitive Sensors." Journal of Materials Chemistry A 12 (24): 14595–607. https://doi.org/10.1039/d4ta00959b.
Hammond, Oliver S., Guillaume Bousrez, Filip Mehler, Sichao Li, Manishkumar R. Shimpi, James Doutch, Leide Cavalcanti, et al. 2023. “Molecular Architecture Effects on Bulk Nanostructure in Bis(Orthoborate) Ionic Liquids." Small 19 (43): 1–11. https://doi.org/10.1002/smll.202300912
Esposito, R., Gallucci, N., Niccoli, M., Cavalcanti, L. P., Russo Krauss, I., Paduano, L., & D'Errico, G. (2023). Synergism and molecular mismatch in rhamnolipid/CTAC catanionic surfactant mixtures. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 674, 131931. https://doi.org/10.1016/J.COLSURFA.2023.131931
Prause, A., Hechenbichler, M., Schmidt, R. F., Prévost, S., Cavalcanti, L. P., Laschewsky, A., & Gradzielski, M. (2023). Modifying the Properties of Microemulsion Droplets by Addition of Thermoresponsive BAB* Copolymers. Langmuir, 39(5), 2022–2035. https://doi.org/10.1021/acs.langmuir.2c03103
Pota, G., Vitiello, G., Venezia, V., Sala, F. Della, Borzacchiello, A., Costantini, A., Paduano, L., Cavalcanti, L. P., Tescione, F., Silvestri, B., & Luciani, G. (2022). Shall We Tune? From Core-Shell to Cloud Type Nanostructures in Heparin/Silica Hybrids. Polymers 2022, Vol. 14, Page 3568, 14(17), 3568. https://doi.org/10.3390/POLYM14173568
Randle, R. I., Fuentes-Caparrós, A. M., Cavalcanti, L. P., Schweins, R., Adams, D. J., & Draper, E. R. (2022). Investigating Aggregation Using in Situ Electrochemistry and Small-Angle Neutron Scattering. Journal of Physical Chemistry C, 126(31), 13427–13432. https://doi.org/10.1021/acs.jpcc.2c03210
Hunvik, K. W. B., Seljelid, K. K., Wallacher, D., Kirch, A., Cavalcanti, L. P., Loch, P., Røren, P. M., Michels-Brito, P. H., Droppa-Jr, R., Knudsen, K. D., Miranda, C. R., Breu, J., & Fossum, J. O. (2022). Intercalation of CO2 Selected by Type of Interlayer Cation in Dried Synthetic Hectorite. Langmuir. https://doi.org/10.1021/acs.langmuir.2c03093
Prause, A., Hechenbichler, M., Schmidt, R. F., Simon, M., Prévost, S., Cavalcanti, L. P., Talmon, Y., Laschewsky, A., & Gradzielski, M. (2022). Rheological Control of Aqueous Dispersions by Thermoresponsive BAB∗ Copolymers of Different Architectures. Macromolecules. https://doi.org/10.1021/acs.macromol.2c01965
Randle, R. I., Cavalcanti, L., Sproules, S., & Draper, E. R. (2022). Aggregate dependent electrochromic properties of amino acid appended naphthalene diimides in water. Materials Advances, 3(7), 3326–3331. https://doi.org/10.1039/d2ma00207h
Karabanova, A., Knudsen, K. D., Berdiyeva, P., Cavalcanti, L. P., Liu, Y., Van Der Pal, M., Deledda, S., & Blanchard, D. (2021). Small-Angle Neutron Scattering Characterization of SrCl2-ENG Composites for Thermochemical Heat Storage. ACS Applied Materials and Interfaces, 13(29), 34213–34226. https://doi.org/10.1021/acsami.1c07449
Michels-Brito, P. H., Cavalcanti, L. P., Fossum, J. O., Malfatti-Gasperini, A., Mayr, L., Puentes-Martinez, X., Tenorio, R. P., Wagner, D. R., Knudsen, K. D., Araki, K., Oliveira, R. G., & Breu, J. (2021). Unmodified clay nanosheets at the air − Water interface. Langmuir. https://doi.org/10.1021/acs.langmuir.0c02670
Wendong, Q., Dent, J., Arrighi, V., Cavalcanti, L., Shaffer, M. S. P., & Shirshova, N. (2021). Biphasic epoxy-ionic liquid structural electrolytes: minimising feature size through cure cycle and multifunctional block-copolymer addition. Multifunctional Materials, 4(3), 035003. https://doi.org/10.1088/2399-7532/AC1EA7
Horwitz, G., Härk, E., Steinberg, P. Y., Cavalcanti, L. P., Risse, S., & Corti, H. R. (2021). The Nanostructure of Water-in-Salt Electrolytes Revisited: Effect of the Anion Size. ACS Nano, 15(7), 11564–11572. https://doi.org/10.1021/acsnano.1c01737
Oliveira, R. G., Paolorossi, M., Cavalcanti, L. P., Malfatti-Gasperini, A., & Montich, G. G. (2021). Periodic bilayer organization in the complexes of Beta-2 Glycoprotein I with anionic lipid membranes. Colloids and Surfaces B: Biointerfaces, 208, 112118. https://doi.org/10.1016/j.colsurfb.2021.112118
Hunvik, K. W. B., Loch, P., Wallacher, D., Kirch, A., Cavalcanti, L. P., Rieß, M., Daab, M., Josvanger, V., Grätz, S., Yokaichiya, F., Knudsen, K. D., Rodrigues Miranda, C., Breu, J., & Fossum, J. O. (2021). CO2Adsorption Enhanced by Tuning the Layer Charge in a Clay Mineral. Langmuir, 37(49), 14491–14499. https://doi.org/10.1021/acs.langmuir.1c02467
Panja, S., Fuentes-Caparrós, A. M., Cross, E. R., Cavalcanti, L., & Adams, D. J. (2020). Annealing Supramolecular Gels by a Reaction Relay. Chemistry of Materials, 32(12), 5264–5271. https://doi.org/10.1021/acs.chemmater.0c01483
Hunvik, K. W. B., Loch, P., Cavalcanti, L. P., Seljelid, K. K., Røren, P. M., Rudić, S., Wallacher, D., Kirch, A., Knudsen, K. D., Rodrigues Miranda, C., Breu, J., Bordallo, H. N., & Fossum, J. O. (2020). CO2Capture by Nickel Hydroxide Interstratified in the Nanolayered Space of a Synthetic Clay Mineral. Journal of Physical Chemistry C, 124(48), 26222–26231. https://doi.org/10.1021/acs.jpcc.0c07206
Michels, L., Da Fonseca, C. L. S., Méheust, Y., Altoé, M. A. S., Dos Santos, E. C., Grassi, G., Droppa, R., Knudsen, K. D., Cavalcanti, L. P., Hunvik, K. W. B., Fossum, J. O., Da Silva, G. J., & Bordallo, H. N. (2020). The Impact of Thermal History on Water Adsorption in a Synthetic Nanolayered Silicate with Intercalated Li+or Na+. Journal of Physical Chemistry C, 124(45), 24690–24703. https://doi.org/10.1021/acs.jpcc.0c05847
Michels-Brito, P. H., Michels, L., Hunvik, K. W. B., Santos, E. C. dos, Pacáková, B., Cavalcanti, L. P., Knudsen, K. D., Bordallo, H. N., & Fossum, J. O. (2020). Experimental methods to study clay minerals and perspective applications of Fluorohectorite. In Materials and Devices (Vol. 5, Issue 1, p. 601). https://doi.org/10.23647/ca.md20201501 (BOOK CHAPTER)
Eş, I., Ok, M. T., Puentes-Martinez, X. E., de Toledo, M. A. S., de Pinho Favaro, M. T., Cavalcanti, L. P., Cassago, A., Portugal, R. V., Azzoni, A. R., & de la Torre, L. G. (2018). Evaluation of siRNA and cationic liposomes complexes as a model for in vitro siRNA delivery to cancer cells. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 555, 280–289. https://doi.org/10.1016/j.colsurfa.2018.06.073
Larsen, S. R., Hansteen, M., Pacakova, B., Theodor, K., Arnold, T., Rennie, A. R., Helgesen, G., Knudsen, K. D., Bordallo, H. N., Fossum, O., & Cavalcanti, L. P. (2018). Sample cell for studying liquid interfaces with an in situ electric field using X-ray reflectivity and application to clay particles at oil – oil interfaces. Journal of Synchrotron Radiation, 25, 1–3. https://doi.org/10.1107/S1600577518004848
Cavalcanti, L. P., Kalantzopoulos, G. N., Eckert, J., Knudsen, K. D., & Fossum, J. O. (2018). A nano-silicate material with exceptional capacity for CO2 capture and storage at room temperature. Scientific Reports, 8(1), 11827. https://doi.org/10.1038/s41598-018-30283-2
Pusterla, J. M., Malfatti-Gasperini, A. A., Puentes-Martinez, X. E., Cavalcanti, L. P., & Oliveira, R. G. (2017). Refractive index and thickness determination in Langmuir monolayers of myelin lipids. Biochimica et Biophysica Acta (BBA) - Biomembranes. https://doi.org/10.1016/j.bbamem.2017.02.005
Franco, M. K. K. D., Araújo, D. R. de, Paula, E. de, Cavalcanti, L., & Yokaichiya, F. (2017). X‐Ray Scattering Techniques Applied in the Development of Drug Delivery Systems. In A. E. B. T.-X. S. Ares (Ed.), X-ray Scattering (p. Ch. 06). InTech. https://doi.org/10.5772/65326 (BOOK CHAPTER)
Schmidt, C., Yokaichiya, F., Doğangüzel, N., Dias Franco, M., Cavalcanti, L., Brown, M., Alkschbirs, M., de Araujo, D., Kumpugdee-Vollrath, M., & Storsberg, J. (2016). An Abraded Surface of Doxorubicin-Loaded Surfactant-Containing Drug Delivery Systems Effectively Reduces the Survival of Carcinoma Cells. Biomedicines, 4(3), 22. https://doi.org/10.3390/biomedicines4030022
Mello, J. C., Moraes, V. W., Watashi, C. M., da Silva, D. C., Cavalcanti, L. P., Franco, M. K., Yokaichiya, F., de Araujo, D. R., & Rodrigues, T. (2016). Enhancement of chlorpromazine antitumor activity by Pluronics F127/L81 nanostructured system against human multidrug resistant leukemia. Pharmacol Res, 111, 102–112. https://doi.org/10.1016/j.phrs.2016.05.032
Akkari, A. C. S., Papini, J. Z. B., Garcia, G. K., Franco, M. K. K. D., Cavalcanti, L. P., Gasperini, A., Alkschbirs, M. I., Yokaichyia, F., De Paula, E., Tófoli, G. R., & De Araujo, D. R. (2016). Poloxamer 407/188 binary thermosensitive hydrogels as delivery systems for infiltrative local anesthesia: Physico-chemical characterization and pharmacological evaluation. Materials Science and Engineering C, 68, 299–307. https://doi.org/10.1016/j.msec.2016.05.088
Balbino, T. A., Serafin, J. M., Malfatti-Gasperini, A. A., De Oliveira, C. L. P., Cavalcanti, L. P., De Jesus, M. B., & De La Torre, L. G. (2016). Microfluidic Assembly of pDNA/Cationic Liposome Lipoplexes with High pDNA Loading for Gene Delivery. Langmuir, 32(7), 1799–1807. https://doi.org/10.1021/acs.langmuir.5b04177
Carvalho, J. M. P., Toniazzo, T., Cavalcanti, L. P., Moraes, I. C. F., Oliveira, C. L. P., & Pinho, S. C. (2015). Physico-chemical stability and structural characterization of thickened multilamellar beta-carotene-loaded liposome dispersions produced using a proliposome method. Colloid and Polymer Science, 293(8), 2171–2179. https://doi.org/10.1007/s00396-015-3594-8
Pires, M. J. M., Macedo, W. A. A., Cavalcanti, L. P., & Carvalho, A. M. G. (2015). Characterization of Fe–Nb sputtered thin films. Journal of Physics and Chemistry of Solids, 86, 36–41. https://doi.org/http://dx.doi.org/10.1016/j.jpcs.2015.06.012
Gasperini, A. A. M., Puentes-Martinez, X. E., Balbino, T. A., De Paula Rigoletto, T., De Sá Cavalcanti Corrêa, G., Cassago, A., Portugal, R. V., De La Torre, L. G., & Cavalcanti, L. P. (2015). Association between cationic liposomes and low molecular weight hyaluronic acid. Langmuir, 31(11), 3308–3317. https://doi.org/10.1021/la5045865
Vieira, C. E. P., Gasperini, A. A. M., Freitas, P. P. S., Oliveira, R. G., & Cavalcanti, L. P. (2015). Characterization of a Pt mirror to be used to deflect synchrotron radiation beam onto Langmuir monolayers. Journal of Synchrotron Radiation, 22(3), 859–861. https://doi.org/doi:10.1107/S1600577515001496
Oshiro, A., da Silva, D. C., de Mello, J. C., de Moraes, V. W. R., Cavalcanti, L. P., Franco, M. K. K. D., Alkschbirs, M. I., Fraceto, L. F., Yokaichiya, F., Rodrigues, T., & de Araujo, D. R. (2014). Pluronics F-127/L-81 Binary Hydrogels as Drug-Delivery Systems: Influence of Physicochemical Aspects on Release Kinetics and Cytotoxicity. Langmuir, 30(45), 13689–13698. https://doi.org/10.1021/la503021c
Balbino, T. a., Aoki, N. T., Gasperini, A. a. M., Oliveira, C. L. P., Azzoni, A. R., Cavalcanti, L. P., & de la Torre, L. G. (2013). Continuous flow production of cationic liposomes at high lipid concentration in microfluidic devices for gene delivery applications. Chemical Engineering Journal, 226, 423–433. https://doi.org/10.1016/j.cej.2013.04.053
Dabkowska, A. P., Talbot, J. P., Cavalcanti, L., Webster, J. R. P., Nelson, A., Barlow, D. J., Fragneto, G., & Lawrence, M. J. (2013). Calcium mediated interaction of calf-thymus DNA with monolayers of distearoylphosphatidylcholine: a neutron and X-ray reflectivity study. Soft Matter, 9(29), 7095–7105. https://doi.org/10.1039/C3SM50350J
Balbino, T. A., Gasperini, A. A. M., Oliveira, C. L. P., Azzoni, A. R., Cavalcanti, L. P., & De La Torre, L. G. (2012). Correlation of the physicochemical and structural properties of pDNA/cationic liposome complexes with their in vitro transfection. Langmuir, 28(31), 11535–11545. https://doi.org/10.1021/la302608g
Cavalcanti, L. P., Tho, I., Konovalov, O., Fossheim, S., & Brandl, M. (2011). Compressibility study of quaternary phospholipid blend monolayers. Colloids and Surfaces B: Biointerfaces, 85(2), 153–160. https://doi.org/10.1016/j.colsurfb.2011.02.015
Trevisan Oliveira, de La Torre, Santana., C. (2011). Technological aspects and scalable enhanced processes for production of functional cationic liposomes as delivery system in gene therapy. In Intech (Ed.), Non viral gene therapy. https://doi.org/10.5772/17869 (BOOK CHAPTER)
Kowarik, S., Gerlach, A., Sellner, S., Cavalcanti, L., Konovalov, O., & Schreiber, F. (2009). Real-time X-ray diffraction measurements of structural dynamics and polymorphism in diindenoperylene growth. Applied Physics A: Materials Science and Processing, 95(1), 233–239. https://doi.org/10.1007/s00339-008-5012-2
Kowarik, S., Gerlach, A., Sellner, S., Cavalcanti, L., & Schreiber, F. (2009). Dewetting of an organic semiconductor thin film observed in real-time. Advanced Engineering Materials, 11(4), 291–294. https://doi.org/10.1002/adem.200800289
Krauss, T. N., Barrena, E., Zhang, X. N., De Oteyza, D. G., Major, J., Dehm, V., Würthner, F., Cavalcanti, L. P., & Dosch, H. (2008). Three-dimensional molecular packing of thin organic films of PTCDI-C 8 determined by surface X-ray diffraction. Langmuir, 24(22), 12742–12744. https://doi.org/10.1021/la8030182
Cavalcanti, L. P., Haas, H., Bordallo, H. N., Konovalov, O., Gutberlet, T., & Fragneto, G. (2007). In situ X-ray and neutron diffraction study of lipid membrane swelling. The European Physical Journal - Special Topics, 141(1), 217–221. https://doi.org/10.1140/epjst/e2007-00043-9
Cavalcanti, L. P., Konovalov, O., & Haas, H. (2007). X-ray diffraction from paclitaxel-loaded zwitterionic and cationic model membranes. Chemistry and Physics of Lipids, 150(1), 58–65. https://doi.org/10.1016/j.chemphyslip.2007.06.219
Kowarik, S., Gerlach, A., Sellner, S., Schreiber, F., Cavalcanti, L., & Konovalov, O. (2006). Real-time observation of structural and orientational transitions during growth of organic thin films. Physical Review Letters, 96(12), 1–4. https://doi.org/10.1103/PhysRevLett.96.125504
Cavalcanti, L. P., Konovalov, O., & Torriani, I. L. (2006). Lipid model membranes for drug interaction study. European Biophysics Journal : EBJ, 35(5), 431–438. http://www.ncbi.nlm.nih.gov/pubmed/16598469
Cavalcanti, L. P., & Torriani, I. L. (2006). Thermotropic phase behavior of DPPC liposome systems in the presence of the anti-cancer agent “Ellipticine." European Biophysics Journal, 36(1), 67–71. https://doi.org/10.1007/s00249-006-0077-3
Kowarik, S., Gerlach, a, Sellner, S., Schreiber, F., Pflaum, J., Cavalcanti, L., & Konovalov, O. (2006). Anomalous roughness evolution of rubrene thin films observed in real time during growth. Physical Chemistry Chemical Physics : PCCP, 8(15), 1834–1836. https://doi.org/10.1039/b517866e
Cavalcanti, L. P., Konovalov, O., Torriani, I. L., & Haas, H. (2005). Drug loading to lipid-based cationic nanoparticles. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 238(1–4), 290–293. https://doi.org/10.1016/j.nimb.2005.06.065
Cavalcanti, L. P., Torriani, I. L., Plivelic, T. S., Oliveira, C. L. P., Kellermann, G., & Neuenschwander, R. (2004). Two new sealed sample cells for small angle x-ray scattering from macromolecules in solution and complex fluids using synchrotron radiation. Review of Scientific Instruments, 75(11), 4541–4546. https://doi.org/10.1063/1.1804956
Filho, U. P. R., Gushikem, Y., Fujiwara, F. Y., De Castro, S. C., Torriani, I. C. L., & Cavalcanti, L. P. (1994). Zirconium Dioxide Supported on a-Cellulose: Synthesis and Characterization. Langmuir, 10(9), 4357–4360.
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