ISIS Deuteration Facility

No
​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​The ISIS Deuteration Facility Laboratory.



 

The ISIS Deuteration Facility is able to produce deuterated samples for neutron experiments.

​Requests for deuterated samples must be made through the ISIS Proposal System when applying for beamtime, but enquiries are encouraged and should be made to ISISDeuterationFacility@stfc.ac.uk to discuss potential requirements.

The lab staff have a wide range of chemical expertise, and the laboratory itself is well equipped with synthetic and analytical equipment.​



Facility Staff Members​​

Dr Peixun Li has many years expertise in synthesising (per)deuterated long-chain molecules up to C20 (including odd-numbered chains), covering fatty acids, alcohols, bromoalkanes, alkyl trichlorosilanes and other related species. In addition, he has considerable experience in the synthesis of (per)deuterated ionic and non-ionic surfactants, such as sodium dodecyl sulfate.

Dr Sarah Youngs has a wide experience of organic synthetic chemistry, including carbohydrate and phosphorous chemistry, and has expertise in the incorporation of (per)deuterated motifs into ionic liquids and custom small molecule synthesis.

Dr James Tellam​ has worked in several diverse areas of organic chemistry and has experience in a wide range of synthetic techniques and methodology development including enantioselectivity, rearrangement protocols and heterocycle synthesis.

Dr K​un Ma received a DPhil degree in Chemistry in 2016 and is now working as a chemist in ISIS Deuteration facility. He has worked in synthesising deuterated fatty acids, ionic and zwitterionic surfactants with different chain length and headgroups.​



No
Yes

Facility Staff Members​

Dr Peixun Li has many years expertise in synthesising (per)deuterated long-chain molecules up to C20 (including odd-numbered chains), covering fatty acids, alcohols, bromoalkanes, alkyl trichlorosilanes and other related species. In addition, he has considerable experience in the synthesis of (per)deuterated ionic and non-ionic surfactants, such as sodium dodecyl sulfate.

Dr Sarah Youngs has a wide experience of organic synthetic chemistry, including carbohydrate and phosphorous chemistry, and has expertise in the incorporation of (per)deuterated motifs into ionic liquids and custom small molecule synthesis.

Dr James Tellam​ has worked in several diverse areas of organic chemistry and has experience in a wide range of synthetic techniques and methodology development including enantioselectivity, rearrangement protocols and heterocycle synthesis.

Dr K​un Ma received a DPhil degree in Chemistry in 2016 and is now working as a chemist in ISIS Deuteration facility. He has worked in synthesising deuterated fatty acids, ionic and zwitterionic surfactants with different chain length and headgroups.​


 

Facility and Equipment

​​



 

Case Studies

Antibody adsorption on the surface of water studied by neutron reflection (mAbs, 2017, 9, 3, 466-475)

​ 

 

Analysis of the asymmetric synergy in the adsorption of zwitterionic-ionic surfactant mixtures. (J. Phys. Chem. B, 2016, 120, 3677-3691)

 

 

 

 

Layering of ionic liquids on a mica surface.

 

A partially deuterated ionic liquid was provided to enable contrast when looking at a film of ionic liquid on a mica surface. (Phys. Chem. Chem. Phys., 2017,19, 297-304)

 



 

Chemical List

​Examples of stock and custom synthesised chemicals produced in the Deuteration Facility

 

Publications

​A list of publications from the Deuteration Facility