ISIS is a world-leading centre for research in the physical and life sciences at the STFC Rutherford Appleton Laboratory near Oxford in the United Kingdom. Our suite of neutron and muon instruments gives unique insights into the properties of materials on the atomic scale. 

We support a national and international community of more than 3000 scientists for research into subjects ranging from clean energy and the environment, pharmaceuticals and health care, through to nanotechnology and materials engineering, catalysis and polymers, and on to fundamental studies of materials.

News and Events

The Indian Minister and ISIS Director
ISIS and India embark on new partnership

Wednesday 13 July 2016

The Indian Minister for Science and Technology and Earth Sciences visited the ISIS Neutron and Muon Source during a trip to the UK to mark the start of new partnerships between the UK and India research communities.

The Rubens’ tube
ISIS Staff Make Waves at the Sci-Tech Daresbury Open Day

Wednesday 13 July 2016

A team from ISIS travelled up to the Daresbury Laboratory in North West England last weekend to showcase the facility at the Sci-Tech Daresbury public open day.

European Spallation Source (ESS), credit: ESS
UK confirmed as founding member of world's largest microscope

Thursday 30 June 2016

The UK has cemented its leading role in designing and delivering the world’s largest microscope, the European Spallation Source (ESS), by being confirmed as a founder member of the project.

ISIS Deputy Director, Zoe Bowd
Up, Up and Away! Tackling the inflationary cost of Helium

Thursday 30 June 2016

At 4pm today, Zoe Bowden, ISIS Deputy Director, opened R108, the new helium recovery building at ISIS. This is the first stage in a cost reduction programme that will see liquid helium from the many cryogenic experiments at ISIS recycled for use elsewhere in the facility as helium gas, which could save the organisation up to £500k per annum.

The liquid nitrogen demonstration was a highlight of the show.
Having a Blast at the Oxfordshire Science Festival

Tuesday 28 June 2016

ISIS dazzled an audience of 70 last weekend at a family show at the Oxfordshire Science Festival.

ISIS Target Station 1
Experiment Reports - we need yours!

Wednesday 06 April 2016

Experiment report forms are an important way we account for beamtime usage at ISIS. They are used by Facility Access Panels to assess follow-up proposals, they help us understand likely outcomes from experiments, and they provide feedback on things we could improve - from experiment equipment to the coffee in Café Zoom!

NMUM 2013
UK Neutron and Muon Science and User Meeting

Tuesday 26 July 2016

The UK Neutron and Muon Science and User Meeting will take place 26-28 July 2016 at Scarman House, Warwick Conference Centre.

Major Instrument and Accelerator Projects

Target Station 2 Phase 2

2015 will see both the capacity and capability of ISIS increase with two new instruments coming online. Target station 2 started operation in 2008 with 7 neutron instruments, and now two new instruments, ChipIR and Larmor have received first neutrons and are beginning their commissioning phases. A further two instruments, IMAT and ZOOM, are under construction.

ISIS First Target Station Project

The ISIS First Target Station (TS1) has now been operating for over 30 years. During this period, there has been no significant work carried out to maintain or develop the internals of TS1. The ISIS First Target Station project aims to refurbish much of TS1 to ensure its continued operation for many years into the future.

TOSCA and MAPS guide projects

Design on the new guides for Maps and Tosca has started with the aim of having the upgraded instruments running sometime in 2016.

Replacement of muon beamline magnets

The ISIS muon facility has been operating since 1987, and some of the muon beamline magnets were second-hand then – they are now over 50 years old in some cases. During the long shutdown in 2014/5, the quadrupoles near the muon target will be replaced.

Linac Tank 4 Replacement

The ISIS linear accelerator (linac) consists of 4 radiofrequency (RF) accelerating tanks, accelerating hydrogen ions generated in the ion source to 37% of the speed of light before feeding them into the synchrotron for final acceleration. Tanks 1 and 4 were built at RAL in 1976, for ISIS’ predecessor, Nimrod. They are now showing their age, so a project is underway to replace tank 4 by 2018.

Refurbishing part of the first target station proton beamline (EPB1)

EPB1 is made up of 68 magnets all of which are roughly 50 years old. Many of the electrical windings of these magnets are deteriorating (especially in high radiation-dose areas near the downstream end of EPB1). Replacement of magnets upstream of the muon target and between the muon target and the neutron target will take place during the 2014/15 shutdown.

Science at ISIS

Bacteria seen under a scanning microscope
Solving the structure of fundamental bacterial protein

Tuesday 24 May 2016

Scientists have discovered the much debated structure of a fundamental bacterial protein, through a combination of neutron and x-ray studies, and computational modelling The protein, known as a single-stranded DNA binding protein (SSB),is involved in a variety of essential DNA mechanisms such as replication and repair. Now the structure of this ‘messy’ protein has been found, it could present a new bullseye for future antibiotics to hit bacteria right at its heart.

Eastern Wood frog
Frozen frog gives clues to improving freeze storage techniques

Thursday 19 May 2016

The Eastern Wood frog’s ability to survive being frozen to temperatures as low as -8°C for weeks in North America is inspiring scientists to investigate how glycerol, nature’s answer to antifreeze, interacts with water to prevent harmful ice crystals from forming. The results are published in the Journal of Physical Chemistry B.

Reducing dependency on fossil fuels
Novel catalyst achieves record-high yields of biofuel

Wednesday 30 March 2016

Scientists have designed a novel catalyst that overcomes the challenge of breaking down complex plant components to produce some of the highest yields of biofuel. In the study, scientists used ISIS to see how a model of the plant material was broken down at the surface of the catalyst. These results bring us one step closer to lessening our dependence on fossil fuels, and are an important development in our shift towards renewable energy.

Joaquín Silvestre-Albero and Mirian Casco on TOSCA
Neutrons reveal potential of MOFs as host structure for methane hydrates

Friday 11 March 2016

Methane storage in the form of gas hydrates, the so-called solid methane storage, has gained an increased interest in the last few years for safe and easy transportation of methane in short and long-distance applications. This approach is inspired in natural methane hydrates that grow in the deep sea and in permafrost under demanding pressure and temperature conditions. Research using TOSCA at the ISIS neutron source has paved the way towards using metal-organic frameworks (MOFs) as a potential platform to promote the nucleation and growth of methane hydrates.

Making an impact

Impact of Neutron Scattering brochure
Neutron Scattering: Materials research for modern life

Thursday 22 November 2012

Read about the social and economic impact of neutron scattering in a new brochure highlighting key examples of the use of the technique.

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